Diabetes mellitus is associated with subnormal serum levels of free testosterone in men

2) and WHR ( > 1) with the presence of subnormal FT and TT levels was performed. RESULTS FT and TT serum levels were subnormal in 46% and 34% of diabetics, respectively, and in 24% and 23% of nondiabetics. Subnormal FT levels were strongly correlated with DM (odds ratio (OR) 2.7; 95% confidence interval (CI) 1.8‐4.1) but not with elevated BMI (OR 1.4; 95% CI 1.0‐2.0). Subnormal TT levels were more strongly associated with elevated BMI and WHR (OR 2.6; 95% CI 1.7‐3.9 and 2.0; 1.4‐2.9) than with DM (1.7; 1.1‐2.6 and 2.0; 1.3‐3.2). CONCLUSION These data strongly suggest that DM is associated with subnormal FT levels, and that TT levels are influenced more by obesity and central adiposity.