In vitro and in vivo Activity of Carbamate-Linked Dual-Action Antibacterial Ro 24-4383

Ro 24-4383 contains desacetylcefotaxime linked by a carbamate bond at the 3′ position to ciprofloxacin. Ro 24-4383 was active against 99% of the 363 gram-positive and gram-negative aerobes tested in v