Incidence, clinical characteristics, risk factors and outcomes of Guillain-Barré syndrome in patients with Covid-19.

We diagnosed 11 Guillain-Barre syndrome (GBS) cases among 71,904 COVID patients attended at 61 Spanish emergency departments (ED) during the 2-month pandemic peak. The relative frequency of GBS among ED patients was higher in COVID (0.15‰) than non-COVID(0.02‰) patients (OR=6.30, 95%CI=3.18-12.5) as was the standardized incidence (9.44 and 0.69 cases/100,000-year, respectively, OR=13.5; 95%CI=9.87-18.4). Regarding clinical characteristics, olfactory-gustatory disorders were more frequent in COVID-GBS than non-COVID-GBS (OR=27.59, 95%CI=1.296-587) and COVID-non-GBS (OR=7.875, 95%CI=1.587-39.09) patients. Although COVID-GBS patients were more frequently admitted to intensive care, mortality was not increased versus control groups. Our results suggest SARS-CoV-2 could be another viral infection causing GBS. This article is protected by copyright. All rights reserved.