Melatonin blood values and total antioxidant capacity in critically ill patients

Endogenous melatonin is decreased in critically ill patients; oral supplementation could help them to cope with sleep disruption and sepsis. Among patients who took part in a trial on melatonin and need for sedation [1], some were studied with blood sampling to describe their melatonin blood values and the relationship with total antioxidant capacity (TAC) in plasma.