Busulfan/cyclophosphamide plus bone marrow transplantation is not sufficient to eradicate the malignant clone in juvenile chronic myelogenous leukemia.

We report here the case of a 29-month-old male who, having experienced early relapse of JCML following busulfan conditioning and HLA-identical BMT, remains in remission more than 2 years after retransplantation following conditioning with TBI