Rofenaid Treatment of Arizona (Paracolon) 7:1,7,8 and Salmonella typhimurium Infections in Young Turkeys

Abstract ROFENAID is the Hoffmann-LaRoche trademark for the compound containing sulfadimethoxine and ormetoprim in a 5:3 ratio. The efficacy of sulfadimethoxine against several species of chicken and turkey coccidia has been demonstrated (Mitrovic and Bauernfeind, 1967; Mitrovic, 1968). Mitrovic (1967) also reported the compound to be effective in preventing fowl cholera and infectious coryza in chickens. Sulfadimethoxine in combination with ormetoprim was reported more effective against coccidiosis than sulfadimethoxine alone (Mitrovic et al., 1969b). This combination product (Rofenaid) was also found to be effective against some common bacterial infections in chickens (Mitrovic et al., 1969a). The present study was undertaken to evaluate the efficacy of Rofenaid against experimentally induced Arizona (paracolon) 7:1,7,8 (AR) and S. typhimurium infections in young turkeys. MATERIALS AND METHODS Five battery trials, each of four weeks duration, involving a total of 1500 poults of the Large, White type, were conducted. Fertile eggs were obtained from a commercial…