Development of Imidazo[1,2-a]pyridine-based probe for detection of hydrazine and its applications in imaging of HepG2 cell

Abstract A novel fluorescent probe IMPD based on imidazo[1,2-a]pyridine for detection of hydrazine was designed and synthesized. This probe used maleimide as the recognition group, which was rapid and sensitive for hydrazine. To compare with our previous probe for hydrazine, this newly probe showed a lower detection limit for 9.1 ppb. In addition, the probe IMPD could dye the HepG2 cell with blue color at the presence of hydrazine.