Metal Hypersensitivity As the Cause of Chronic Fatigue Syndrome: Case Report

Chronic fatigue syndrome (CFS) is a pattern of symptoms manifested in persistent fatigue for more than 6 months, and it can reduce daily activity by more than 50%. Its prevalence, according to various criteria, is 0.03-0.2%. It is 4-6 times more common in women than in men and the typical sufferer is 40-59 years old. Potential consequences include infections, immuno-deficiency, neurocereberal pathologies, and even hormonal dysregulations. There is much evidence for environmental influences on its development. These include highly reactive metal ions slowly released by corrosion from dental fillings and other metal-containing artificial body implants, as well as products used daily, drugs and vaccines (including metal adjuvants). In sensitive persons, these can activate Tlymphocytes and trigger a chronic systemic inflammatory reaction which produces cytokines and increases oxidative stress.