GW29-e1322 Probucol and anisodamine prevents contrast induced nephropathy in diabetic rats by inhibiting Akt/mTOR/P70S6K signaling pathways

Apoptosis is recognized as an important mechanism in contrast-induced nephropathy (CIN). As probucol and anisodamine have been found to be renoprotective and anti-apoptotic in multiple kidney injuries, we hypothesized that they would prevent CIN. The objective of this research is to study the