Passive smoke exposure was related to mean platelet volume in never-smokers.

OBJECTIVE: To investigate the effect of passive smoking on the changes in mean platelet volume (MPV) in healthy adults. METHODS: Participants (N = 17,825) were drawn from the Dongfeng-Tongji cohort. Multiple logistic regression analysis was used to examine relationships between MPV and selected variables among subgroups of MPV clarified by the MPV reference range for Chinese adults. RESULTS: Female never smokers exposed to passive smoke ≥ 60 minutes every day (OR: 1.471, 95%CI: 1.147-1.886) or ≥ 30 years had a higher risk of having low MPV (OR: 1.260, 95%CI: 1.004-1.583). CONCLUSIONS: Certain duration of passive smoke exposure (≥ 60 minutes/day or ≥ 30 years) was associated with higher risk of having low MPV in female never smokers.