Влияние биокомпозитного материала Остеоматрикс на процессы регенерации костной ткани в условиях эксперимента (иммуногистохимическое исследование)

The results of experimental study on the macroand micropreparations of biocomposite bone graft Osteomatrix when replacing the femoral defects in rats using immunohistochemical method and light microscopy are provided. Dynamics of the researches 3 months. We have studied immunohistochemical and histomorphological features of restructuring bone implants, developed an experimental model for transplantation of bone implants in laboratory animals. Information value of immunohistochemical study for an objective evaluation of bone remodeling rate and its response to the implant has been demonstrated. This method helps to identify reliably osteoinductive proteins, as well as to quantify level of their expression.