A review of chemical components and pharmacological effects of Kelussia odoratissima Mozaff

Kelussia odoratissima Mozaff. is a perennial aromatic herb, which grows up to 120 to 200 cm high. The flowers are 1 to 2 mm in diameter, all hermaphrodites and petals are yellow and produced in compound umbels. While this plant has lots of properties, the aim of this study is to overview its therapeutic, nutritive and industrial effects. This review article was carried out by searching studies in PubMed, Web of Science, and Iran Medex databases up to 2015. The search terms were “Kelussia odoratissima Mozaff.”, “therapeutic”, ''pharmacological”, “keluss”, “karafs e koohi”, ”wild celery” or their combinations. Totally, of 100 found articles, 47 articles (42 in vitro and 5 in vivo) were included. Various studies have shown that Kelussia odoratissima Mozaff. has antioxidant, antibacterial and anti-fungi, larvicidal and insecticidal, anti-cancer, antimicrobial, sedative, anxiolytic, analgesic, anti-spasm, anti-inflammatory, anti-hyperlipidemic, anti- hypercholesterolemic, antigenotoxic and fibrinolytic properties.Kelussia odoratissima Mozaff. is widely used for therapeutic and purposes that trigger its significant value. Various combinations and numerous medicinal properties of its extract, essential oils, its stems and leaves demand further and more scientific studies about the effective compounds this plant and their mechanism actions.