Diagnostic significance of Tl-201-Ga-67 discordant pattern of biodistribution in AIDS.

Galllum-67 citrate imaging is a valuable part of the clinical evaluation of HIV-seropositive patients in spite of some specificity-related limitations. However, its role in the detection of pulmonary and extrapulmonary Kaposi sarcoma is known to be extremely limited. Uptake of TI-201 chloride has been demonstrated in uncomplicated lung lesions of Kaposi sarcoma. An AIDS patient with multiple sarcomatous skin lesions, bilateral cervical and inguinal adenopathies, bibasilar lung infiltrates, and clinical evidence of a superior vena cava syndrome is presented. The discordant pattern of TI-201-Ga-67 biodistribution in this patient was consistent with disseminated Kaposi sarcoma lymphadenopathies