Paired exome analysis of Barrett's esophagus and adenocarcinoma

Matthew D. Stachler,Amaro Taylor-Weiner,Shouyong Peng,Aaron McKenna,Agoston T. Agoston,Robert D. Odze,Jon M. Davison,Katie S. Nason,Massimo Loda,Ignaty Leshchiner,Chip Stewart,Petar Stojanov,Sara Seepo,Michael S. Lawrence,Daysha Ferrer-Torres,Jules Lin,Andrew C. Chang,Stacey Gabriel,Eric S. Lander,David G. Beer,Gad Getz,Scott L. Carter,Adam J. Bass

Paired exome analysis of Barrett's esophagus and adenocarcinoma

2015

Adam Bass, Gad Getz, Scott Carter and colleagues report the whole-exome sequences of 25 pairs of esophageal adenocarcinoma and Barrett's esophagus. They identify two pathways by which Barrett's esophagus can develop into esophageal adenocarcinoma.

Keywords:

Genetics
Exome
Esophagus
Barrett's esophagus
Biology
Adenocarcinoma
esophageal adenocarcinoma

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