Stereoselective Synthesis of 1′β‐2′,3′‐Dideoxy‐2′‐bis(ethoxycarbonyl)methyluridine Nucleosides by Ring Opening of Cyclopropanated Glycals.

Cyclopropanations of glycals followed by Lewis acid-mediated glycosylations with 5-substituted uracils afforded 1′β-2′,3′-dideoxy-2′-bis(ethoxycarbonyl)methyluridine nucleosides in a highly regiospecific and stereoselective manner in good yields.