Quick-disintegration tablets of calcium atovastatine, and its preparation method

A rapidly disintegrating tablets of atorvastatin calcium and preparing method belongs to the technical field of medicine, for solving atorvastatin calcium delayed disintegration of the tablet, the problem of slow dissolution. The tablets of atorvastatin calcium and a carrier, the components by weight% was prepared as follows: atorvastatin calcium 5-25%, disintegrant support consists essentially of 45-55%, flavoring agent 1 5%, 25-50% filler, 1-3% lubricant composition. The present invention, by experiment, the disintegrant selection, usage and dosage are explored to determine the species and the disintegrant, the ratio of the applied, so that the effect is optimized. Seen from the test results, the degree of disintegration, dissolution have been significantly improved or improved, having good dispersion state, short disintegration time and rapid drug dissolution, rapid absorption, high bioavailability, and convenient to take.