The lateral mobility of some membrane proteins is determined by their ectodomains

Fen Zhang,* Bruce Crise,§ Bing Su,* Yu Hou,* John K. Rose,§ Alfred Bothwell,1I and Ken Jacobson** *Department of Cell Biology and Anatomy and lLineberger Cancer Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599; §Departments of Pathology and Cell Biology, Yale University School of Medicine, New Haven, Conneticut 06514; "Section of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Conneticut 06510 USA