Cognitive and behavioral status in Japanese ALS patients: a multicenter study

Yasuhiro Watanabe,Joost Raaphorst,Yuishin Izumi,Hiide Yoshino,Satoru Ito,Tadashi Adachi,Hiroshi Takigawa,Michihito Masuda,Naoki Atsuta,Yoshiki Adachi,Sagiri Isose,Kimihito Arai,Osamu Yokota,Masaya Oda,Mieko Ogino,Hiroo Ichikawa,Kazuko Hasegawa,Hideki Kimura,Toshio Shimizu,Ikuko Aiba,Hayato Yabe,Makoto Kanba,Kimiyoshi Kusumi,Tetsuya Aoki,Yu Hiroe,Hirohisa Watanabe,Kazutoshi Nishiyama,Masahiro Nomoto,Gen Sobue,Emma Beeldman,Ritsuko Hanajima,Kenji Nakashima

Cognitive and behavioral status in Japanese ALS patients: a multicenter study

2020

Objectives Amyotrophic lateral sclerosis (ALS) patients may present with cognitive and behavioral abnormalities similar to frontotemporal dementia (FTD). In this multicenter study we examined Japanese ALS patients with and without FTD in order to characterize the full extent of cognitive and behavioral abnormalities, including associations with functional motor status, anxiety and depression.

Keywords:

Physical therapy
Frontotemporal dementia
Anxiety
Diabetes mellitus
multicenter study
Amyotrophic lateral sclerosis
Medicine
Cognition
Pediatrics
Audiology
Age of onset
Montreal Cognitive Assessment
Hospital Anxiety and Depression Scale
Verbal fluency test

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