Опыт применения метотрексата для подкожного введения у пациентки с ранним полиартикулярным ювенильным идиопатическим артритом

This article presents a case of severe course of polyarticular juvenile idiopathic arthritis. Active articular syndrome, high laboratory parameters of disease activity, severe incompetence were observed in a child by the therapy initiation. Successful use of intramuscular methotrexate in the dose of 15 mg/m 2 of body surface per week is described. Exudative articular alterations, arthralgiae, morning stiffness duration reduced as early as one month after the therapy initiation in a child. Acute inflammatory articular alterations cut off, range of motions recovered completely in 4 out of the 6 affected joints, laboratory parameters of disease activity reduced and normalized (ESR and CRP), inactive disease stage was registered after 6 months of treatment. We did not observe any undesirable phenomena in the setting of methotrexate therapy.