Sub-Acute Thyroiditis-Presenting as Pyrexia of Unknown Origin-A Case Series
2021
The differential diagnosis for Pyrexia of Unknown Origin (PUO) remains extensive. The most common PUO categories
are infectious, neoplastic, rheumatic, and inflammatory. It is important to remember that PUO is far more often caused
by an atypical presentation of a rather common disease than by a very rare disease. We report a series of cases of
patients with subacute thyroiditis presenting as PUO.
Discussion/Conclusion: All reported cases of PUO had similar
findings in each of the patients, well-documented as subacute thyroiditis. Sub-acute thyroiditis should be considered
in the diagnostic workup of PUO even in the absence of overt toxic symptoms of thyroid hormone excess. Early
recognition and timely anti-inflammatory therapy may help in successful management.
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