Parenteral acyclovir therapy for cytomegalovirus infection after renal transplantation.

: Three patients who had received cadaveric renal transplants developed fevers within three months of transplantation. Concurrent cytomegalovirus infection was confirmed by virological studies. In all three patients there was both a clinical and virological response to a five day course of intravenous acyclovir. In one patient the dose required to produce this response was 5 mg/kg/day; however two patients required 10 mg/kg/day. All three patients remain well after 8-12 months follow-up.