The association of prostaglandins E2 and F2α with erythropoiesis regulatory factors

Abstract Prostaglandins E 2 and F 2α have regulatory roles, respectively, in the potentiation and inhibition of erythropoietin. Antisera to PGF 2α and EIF, an erythropoiesis inhibitory factor, can be used to resolve the reason for improvement in erythropoiesis following renal dialysis. Concurrent loss of PGE 2 with Ep during treatment with neuraminidase suggests that PGE 2 is bound to Ep by way of sialic acid.