Preventing Coronary Restenosis after Stent with ~(188)Re Liquid-Filled Balloon

Objective To investigate the clinical safety, effect and feasibility of preventing restenosis after stent with ~(188)Re liquid-filled balloon. Methods Seven patients underwent coronary stenting underwent brachytherapy with ~(188)Re liquid-filled ballon. All patients performed radionuclide gated myocardial perfusion imaging before, (within) one week and six months after brachytherapy respectively for the assessment of restenosis.(Results )The time duration of radiation exposure in brachytherapy was (6.20±1.55) min in average. Non of the patient occurred serve side effect during procedure including balloon rapture,leakege of the ~(188)Re radioactivity into circulation events etc. The incidence of restenosis within the stent was 14.3% (1/7). Conclusion The brachytherapy using ~(188)Re liquid-filled balloon was a safe, effective and feasible method in preventing restenosis within stent and also it has important clinical value.