A SINGLE PARTICLE ENCAPSULATION WITHIN DROPLET IN ARRAY-BASED MICROFLUIDIC PLATFORM

In this paper, we describe a passive single particle encapsulation within a droplet using array-based microfluidic platform. In order to trap a single particle into an array of well where a droplet is created, the hydrodynamic resistances of by-passing channel and trapping channel are calculated. By the hydrodynamic resistance, the particles are successfully trapped into the array of the wells. Subsequently, air and immiscible oil were induced to create droplets encapsulating the particles. By applying backward flow, the droplets were released for a post processing. We expect that the proposed method can be applicable in studying a single cell analysis.