Simple and efficient method for producing high radionuclidic purity 111In using enriched 112Cd target.

Abstract In this work, a simple and efficient method for producing high radionuclidic purity 111In from an enriched 112Cd target was developed. The enriched 112Cd metal target formed by cyanide-free electroplating was bombarded with protons of 21 MeV in a CS-30 cyclotron. Then, we explored a purification scheme using CL-P204 cation exchange resin wherein 98% of the 111In in the bombarded target could be extracted in less than 1 h. The purified 111In in the form of [111In]In-chloride had a high radionuclidic purity (99.9%) and a low impurity concentration (