Four Color Fret Dye Nucleotide Terminators for DNA Sequencing

T. Sudhakar Rao,Satyam Nampalli,Kate Lavrenov,Weihong Zhang,Haiguang Xiao,John H. Nelson,Shiv Kumar

Four Color Fret Dye Nucleotide Terminators for DNA Sequencing

2001

T. Sudhakar Rao
Satyam Nampalli
Kate Lavrenov
Weihong Zhang
Haiguang Xiao
John H. Nelson
Shiv Kumar

The synthesis of four color set of energy transfer-dye terminators (8a–8d) starting from p-iodo-β-phenylalanine was accomplished and their utility in the sequencing reactions has been evaluated.

Keywords:

Nucleotide
Nucleic acid
DNA sequencing
Förster resonance energy transfer
Biochemistry
Chemistry
Organic chemistry

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