Noncoding RNA in Gastric Cancer with Potential Prognostic and Predictive Role

Noncoding RNAs (ncRNAs) have attracted considerable attention in cancer pathology. ncRNAs are involved in different cellular processes such as development, proliferation, differentiation, and apoptosis. The dysregulation of ncRNAs has been reported in tumor initiation, progression, invasion, and metastasis in various cancers, including gastric cancer (GC). In the past few years, several studies have focused their attention on the understanding of these molecules, and several emerging ncRNAs could have a prognostic and predictive role in cancer. ncRNAs include mRNAs, microRNAs (miRNAs), long ncRNAs (lncRNAs), and circular RNAs (circRNAs), which play critical roles in the tumorigenesis of GC. This chapter includes the latest information and findings related to ncRNAs and their possible therapeutic use.