Applying Molecular Communication Theory to Multi-Scale Integrated Models of Biological Pathways

The natural communication ability of cells is explored in this paper by providing preliminary results in the estimation of the Mutual Information (MI) of signaling pathway communication channels. These results, based on an application of Molecular Communication (MC) and information theory concepts to multi-scale integrated Flux-Balance Analysis (iFBA) models are a first step to evaluate the potential of cells and their biochemical processes as a substrate for enabling engineered MC channels for the future internet of Bio-Nano Things.