Abstract 20696: Platelet-Lymphocyte Ratio Predicts Long Term Mortality in Patients Undergoing Coronary Angiography

Introduction: Inflammation and thrombocytosis play an important role in the progression of atherosclerosis and coronary artery disease (CAD). We have previously shown that platelet-lymphocyte ratio (PLR) is an independent predictor of presence of CAD in patients aged 55 years or older. Previous studies demonstrated the association between PLR and cardiovascular prognosis. Hypothesis: We hypothesize that PLR predicts long term mortality in patients undergoing coronary angiography, regardless of presence of CAD. Methods: We followed up 525 patients from the BRAVEHEART cohort who were referred for coronary angiography at our institution for a mean period of 5.0±1.3 years. The primary outcome was all-cause mortality. Patients were classified into tertiles based on their pre-angiogram PLR values ( 145.6). Results: There were 53 deaths over the follow-up period and patients in tertile3 (PLR>145.6) had worse prognosis compared with patients in tertile1 and tertile2 (29, 12 and 12 deaths resp...