Суточные изменения центральной гемодинамики у больных хронической сердечной недостаточностью с ночными приступами одышки

Aim. To study daily changes of central hemodynamics (CHD) in patients with chronic heart failure (CHF) and the effects of therapy Materials and methods. 22 patients with ischemic heart disease and CHF of III-IV functional class (FC) by NYHA, age 60,5±10,5 were observed Patients were suffering from night-time dyspnoea attacks and had pulmonary artery occlusion pressure (PAOP) 1 5-20 mm Hg. CHD was monitored invasively before the treatment and after 4 weeks of CHF treatment. Results. According to the cardiac index (CI) at admission patients were split into two groups. 9 patients of group-l had CI 2, and 13 patients of group-ll had CI >2,1 5 l\min\m2 In patients of group-l CI increased in 4 weeks of treatment. The treatment caused considerable clinical improvement in all patients. The CHD indexes also improved. Initially evening-night-time peaks of PAOP (p2 treatment results in the normalization of CHD and its daily rhythm. In patients with CHF with initial CI >2,1 5 l\min\m2 the treatment leads to the normalization of CHD, though it doesn't correct daily rhythm disturbances of circulation