Correlation Between Gingival Crevicular Fluid Hemoglobin Content and Periodontal Clinical Parameters.

Background: Probing depth (PD) and bleeding on probing (BOP) are essential clinical parameters used for periodontal diagnosis. This study investigated whether detection of hemoglobin (Hb) in gingival crevicular fluid (GCF), along with PD and BOP, would improve diagnostic accuracy.Methods: After plaque index (PI) was measured, GCF was collected from the gingival sulci of 401 anterior teeth in the maxilla and mandible from 184 patients who had entered periodontal maintenance therapy. Clinical parameters (gingival index [GI], PD, clinical attachment level [CAL], and BOP) were recorded. Hb values in GCF were assessed by immunochromatography. Moreover, cutoff values for PI, GI, and CAL based on the degree of PD and amount of GCF were created and analyzed.Results: Hb was detected in 64.8% of GCF samples in 105 BOP-negative (–) sites in the periodontally stable group out of 107 sites that were less than all cutoff values. There were 71 BOP(–) sites in the periodontal-management-required group out of 122 sites th...