IDDF2021-ABS-0020 A survival analysis of chinese patients with gastrointestinal mucosal melanomas: a single-center retrospective study

Background Mucosal melanomas are highly malignant tumors, while are of great interest due to their aggressive behavior and less favorable prognosis, which could be the result of many reasons, for example, late diagnosis, patients’ delay and the obscured anatomic site of origin. We, in this paper, do a retrospective study to investigate the characteristics and prognosis of gastrointestinal mucosal melanomas in a Chinese population to help future clinic doctors to recognize the prognosis of the disease. Methods We retrospectively studied 49 patients diagnosed with gastrointestinal mucosal melanomas. Multivariate analyses of prognosis and the overall survival (OS) were performed using the Cox proportional hazard model. Results Multivariate analyses show that the number of the lesions (P=0.006, IDDF2021-ABS-0020 Figure 1. OS curves according to tumour location (Cox proportional hazards model)), the lymph nodes metastasis (P Conclusions The condition of primary or metastatic tumors, the anatomic sites in the gastrointestinal tract, and the lymph nodes metastasis may be the independent factors that affect the prognosis of patients with gastrointestinal mucosal melanomas. This study is expected to provide some clues for future exploration which will help clinicians improve the accuracy of judging prognosis.