MEASUREMENT OF COLCHICINE BY ANODIC VOLTAMMETRY WITH CARBON PASTE ELECTRODE

Colchicine is determined by anodic voltammetry using a carbon paste electrode (graphite powder∶paraffin liquid=1 5∶1) in 0 05 mol·L -1 H 2SO 4, with a linear range of 4 0×10 -7 ～1 0×10 -3 mol·L -1 , detection limit 1×10 -7 mol·L -1 . Two waves at 1 07 and 1 33 V vs SCE were observed in the anodic scan, peak potential is increased with pH. The raw material and tablets of colchicine have been analysed with good results.