A systematic analysis on DNA methylation and the expression of both mRNA and microRNA in bladder cancer

Jialou Zhu,Zhimao Jiang,Fei Gao,Xueda Hu,Liang Zhou,Jiahao Chen,Huijuan Luo,Jihua Sun,Song Wu,Yonghua Han,Guangliang Yin,Maoshan Chen,Zujing Han,Xianxin Li,Yi Huang,Weixing Zhang,Fangjian Zhou,Tong Chen,Pingping Fa,Yong Wang,Liang Sun,Huimin Leng,Feng-hao Sun,Yuchen Liu,Mingzhi Ye,Huanming Yang,Zhiming Cai,Yaoting Gui,Xiuqing Zhang

A systematic analysis on DNA methylation and the expression of both mRNA and microRNA in bladder cancer

2011

Background DNA methylation aberration and microRNA (miRNA) deregulation have been observed in many types of cancers. A systematic study of methylome and transcriptome in bladder urothelial carcinoma has never been reported.

Keywords:

Gene expression profiling
Urothelium
microRNA
Locus (genetics)
DNA methylation
Transcriptome
Bladder cancer
Messenger RNA
Molecular biology
Biology
Bisulfite sequencing
Gene
Gene expression

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