Age differences in the adherence to treatment guidelines and outcome in patients with ST-elevation myocardial infarction

Abstract The aim of this study was to assess age differences in the utilization of class-I treatment guidelines and its effect on mortality in patients with ST-elevation myocardial infarction (STEMI). The study included 1026 consecutive patients from the prospective nationwide Acute Coronary Syndrome Israeli Survey (ACSIS). Primary reperfusion was used less often among elderly (age > 75 years) patients than among those aged 65–74 and p (for trend) = 0.004). Class-I evidence-based medications (EBM) at discharge (aspirin, β-blockers, angiotensin converting-enzyme inhibitors = ACEI, angiotensin receptor-blockers = ARBs and statins) were less frequently prescribed to elderly compared to younger age-subgroup (44%, 61%, 57%, respectively; adjusted odds ratio (OR) = 0.62; 0.40–0.97 for age ≥ 75 vs. age