New Triterpenoid Saponins from Gynostemma pentaphyllum

Three new triterpenoidal saponins (1−3), together with the known compound 4, were isolated from a MeOH extract of the aerial parts of Gynostemma pentaphyllum. Their structures were elucidated on the basis of chemical and spectral methods, such as 1H−1H DQFCOSY, HMQC, HMBC, and TOCSY NMR spectra. The aglycon moiety of 1 and 2 is a new dammarane-type triterpene 12-oxo-2α,3β,20(𝒮)-trihydroxydammar-24-ene.