0896. Temporal changes in tidal recruitment compared to histologic outcome in experimental acute respiratory distress syndrome

Acute Respiratory Distress Syndrome (ARDS) and Ventilator-Associated Lung Injury (VALI) are characterized histologically by Diffuse Alveolar Damage (DAD)1. Tidal recruitment (TR) of nonaerated airspaces during mechanical ventilation (MV) causes VALI. Different MV strategies aim to reduce TR and VALI by individualized PEEP2-4.