A decisional algorithm to start iron chelation in patients with beta thalassemia

Since the implementation of deferrioxamine for the treatment of thalassemia major, it has been customary to initiate chelation after the first 10–20 transfusions or when serum ferritin reached over 1000 mcg/L.[1][1] However, in non-chronically-transfused thalassemia patients, ferritin