Light propagation in biological tissue

Abstract We developed a new parallel computational method for solving fluorescence and elastically scattered light propagation through a biological tissue illuminated by a collimated incident beam. The three-dimensional steady state radiative transfer equation was solved using a Modified Finite Volume Method with a cell-vertex formulation. An Exponential spatial differencing scheme was used to efficiently lessen the false scattering. Several test problems are presented to assess the performance and accuracy of the numerical Method. We show that it is possible to obtain a very good level of accuracy. Relative differences less than 1.5% were obtained in comparison with the Monte Carlo reference solution for the selected problems. This study shows the potential of the proposed computational method to be used as an accurate deterministic forward solver in Optical Tomography.