Estimation of CYP2C19 activity by the omeprazole hydroxylation index at a single point in time after intravenous and oral administration
2007
Objective
The purpose of this study was to identify the common time point to achieve hydroxylation index (HI: omeprazole plasma concentration/5-hydroxyomeprazole plasma concentration) reflecting AUCOPZ/AUC5OH-OPZ after intravenous (IV) and oral (PO) administration.
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