Assessment of thrombotic events in children: A hospital based study

Background: There is scarcity of information on the incidence of inherited thrombophilia from our country. The present study was conducted to assess thrombotic events in children. Materials & Methods: The present study was conducted in the department of Pediatrics. It comprised of 38 children. Patients were subjected to complete hemogram, sickling test, immunological evaluation etc. Risk factors for thrombotic events were recorded. Results: Out of 38 patients, 16 were of VTE and 22 were of ATE. The most common VTE was due to central venous catheter seen in 6 cases. Most common ATE was due to thrombophilias seen in 5 cases. Other reasons in VTE were immobilization seen in 2, trauma in 1, infections in 2, dehydration in 2. Other reasons in ATE were immobilization seen in 2, trauma in 4, infections in 3, dehydration in 3 and unknown in 4 cases. The difference was significant (P< 0.05). Conclusion: Thrombotic events in children are emerging problem. The most common reason for VTE was central venous catheters and in ATE was thrombophilias.