Analysis of the mechanisms of action of isopentenyl caffeate against Leishmania.

Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES – Financial code 001), Fundacao de Apoio a Pesquisa e Inovacao (FAPITEC/SE), (PROCESSO: 88887.159533/2017-00 extracao, encapsulacao e caracterizacao de bioativos para o interesse biotecnologico), Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq 301964/2019-0 Chamada 06/2019, and Chamada CNPq no 01/2019), Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ) for financial support. The authors thank Denise da Rocha de Souza, who is supported by a FAPERJ scholarship, for technical assistance. EBS wishes to acknowledge the Portuguese Science and Technology Foundation (FCT/MCT) and European Funds (PRODER/COMPETE) for the project UIDB/04469/2020 (strategic fund), co-financed by FEDER, under the Partnership Agreement PT2020