Eff ect of Soy Protein on Blood Lipid Concentration in China: a Randomized Controlled Trial

We conducted a randomized controlled trial to verify the serum lipid lowering eff ect of ingesting a test food containing β‑conglycinin (a constituent of soy protein in China. One hundred women aged 40‑65 years old with abnormal blood lipid participated the trial. Participants were randomly allocated to three groups of placebo (n=34 4 casein tablets a day low dose (n=33 4 tablets containing 2.3 g β ‑conglycinin and high dose (n=33 8 tablets containing 4.6 g with balanced age baseline weight and serum lipids. All participants were instructed to take the test tablets two times a day and not to change their daily life style including diet and sports. The ages baseline weight and serum lipids of participants did not differ among the three groups. The serum triacylglycerol (TG of the low dose group after 6 weeks (2.76±0.77 mean±SD significantly decreased by 0.44 mmol/L (14.5% from the baseline (p=0.000 which was also significantly lower than that of the placebo group (p=0.000; furthermore the TG of the low dose group after 12 weeks (2.41±0.78 decreased significantly by 0.78 mmol/L (21.7% from the baseline (p=0.000 which was also significantly lower than that of the placebo