Lung Deposition of a Radiolabeled Aerosol With Two Ventilation Modalities During Invasive Mechanical Ventilation: A Randomized Comparative Study

Volume-controlled ventilation has been suggested during nebulization to optimize lung deposition although promoting spontaneous ventilation is targeted for ventilated patient management. Comparing topographic lung aerosol deposition during volume-controlled and spontaneous ventilation in pressure support has never been performed.