The reference model uses object oriented population generation

The Reference Model for disease progression is a league of models attempting to explain published study data. The model cross references simulation results with observed clinical results for multiple population cohorts. The model has grown to contain 47 different cohorts from 9 diabetic populations. Each population contains -40 rules and ~45 objectives. Since there are many repetitions and replications in the code, it becomes hard to maintain and expand further. To support future expansion, code reusability is needed. This is accomplished by an object oriented approach that allows inheriting population generation building blocks. The presentation will discuss the reorganization of population generation using the MIcro Simulation Tool - MIST. Examples demonstrating the benefit from the transformation towards the object oriented approach are presented. Results demonstrate model stability after code transformation.