Matrix molecular antigen presenting a beta amyloid.

A composition comprising: (a) a non-natural molecular scaffold comprising: (i) a core particle, wherein said core particle is a virus particle of a RNA phage type; (Ii) an organizer comprising at least one first attachment site, wherein said organizer is connected to said core particle by at least one covalent bond; (B) an antigen or antigenic determinant with at least one second attachment site, wherein said antigen or antigenic determinant is amyloid beta peptide (Abeta1-42) or a fragment thereof, and wherein said second attachment site is selected from the group It is consisting of: (i) an attachment site not naturally occurring with the said antigen or antigenic determinant; and (ii) an attachment site naturally occurring with said antigen or antigenic determinant, wherein said second anchoring site susceptible association through at least one non-peptide to said first anchoring site link; and wherein said antigen or antigenic determinant and said scaffold interact through said association to form an ordered and repetitive array antigen.