HIV-1 Protease and Reverse-Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance

Soo-Yon Rhee,W. Jeffrey Fessel,Andrew R. Zolopa,Leo B. Hurley,Tommy F. Liu,Jonathan Taylor,Dong Phuong Nguyen,Sally Slome,Daniel Klein,Michael A. Horberg,Jason Flamm,Stephen Follansbee,Jonathan M. Schapiro,Robert W. Shafer

HIV-1 Protease and Reverse-Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance

2005

Soo-Yon Rhee
W. Jeffrey Fessel
Andrew R. Zolopa
Leo B. Hurley
Tommy F. Liu
Jonathan Taylor
Dong Phuong Nguyen
Sally Slome
Daniel Klein
Michael A. Horberg
Jason Flamm
Stephen Follansbee
Jonathan M. Schapiro
Robert W. Shafer

Background It is important, for drug-resistance surveillance, to identify human immunodeficiency virus type 1 (HIV-1) strains that have undergone antiretroviral drug selection.

Keywords:

Drug resistance
Virus
Drug
HIV-1 protease
Virology
Nucleoside Reverse Transcriptase Inhibitor
Immunodeficiency
Immunology
Medicine
Reverse transcriptase
Lentivirus
Mutation
proteolytic enzymes

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