Quantitative methylation analysis of HOXA3, 7, 9, and 10 genes in glioma: association with tumor WHO grade and clinical outcome

Angela Di Vinci,Ida Casciano,Elena Marasco,Barbara Banelli,Gian Luigi Ravetti,Luana Borzì,Claudio Brigati,Alessandra Forlani,Alessandra Dorcaratto,Giorgio Allemanni,Gianluigi Zona,Renato Spaziante,Henning Gohlke,Giovanni Gardin,Domenico Franco Merlo,Vilma Mantovani,Massimo Romani

Quantitative methylation analysis of HOXA3, 7, 9, and 10 genes in glioma: association with tumor WHO grade and clinical outcome

2012

Angela Di Vinci
Ida Casciano
Elena Marasco
Barbara Banelli
Gian Luigi Ravetti
Luana Borzì
Claudio Brigati
Alessandra Forlani
Alessandra Dorcaratto
Giorgio Allemanni
Gianluigi Zona
Renato Spaziante
Henning Gohlke
Giovanni Gardin
Domenico Franco Merlo
Vilma Mantovani
Massimo Romani

Purpose The purpose of this study was to determine whether specific HOXA epigenetic signatures could differentiate glioma with distinct biological, pathological, and clinical characteristics.

Keywords:

Methylation
DNA methylation
Glioma
HOXA3
DNA
Gene
Immunology
Pathology
Epigenetics
Central nervous system disease
Biology
Hematology
Survival rate
Pathological
Internal medicine
Gene duplication

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