A CASE OF COLONY STIMULATING FACTOR PRODUCING LEIOMYOSARCOMA OF THE ILEUM

This report describes one autopsy case of colony stimulating factor producing leiomyosarcoma of the ileum. A 74-year-old man was admitted to our hospital with a loss of appetite and epigastralgia. At admission patient had a dilated chest subcutaneous veins, axilla and inguinal lymphnode swelling, and a huge tumor in the left abdomen. Blood chemical examinations resulted in the white blood cell count of 22500 mm3, serum LDH of 825 IU, and ALP of 24.6 KAU. CT revealed a giant mass in the abdomen and angiography showed a tumor stain in the mesentery, but no abnormality was found by enema. There was no passage disturbance in the upper gastrointestinal tract. After admission the condition of the patient abruptly wortheded, and he died on the 20th hospital day. Autopsy disclosed that the tumor was leiomyosarcoma of the ileum. Immunochemical stainning using polyclonal CSF antibody was weakly positive in the tumor tissues.