Characterization of the interaction between two Anti-viral drugs and Egg albumin

The binding of two anti-viral drugs (1. Quercetin [Q] and 2. Amantadine [A]) to Egg albumin [EA] was investigated by fluorescence spectroscopy under simulation of physiological conditions. The quenching mechanism was suggested according to the fluorescence measurement. The Stern-Volmer quenching constants were determined. In addition, binding constants were also calculated at room temperature.